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سه شنبه, 28 آبان 1404 17:58
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سه شنبه, 28 آبان 1404 17:58
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سه شنبه, 28 آبان 1404 17:58
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سه شنبه, 28 آبان 1404 17:53
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سه شنبه, 28 آبان 1404 17:52
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سه شنبه, 28 آبان 1404 17:52
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سه شنبه, 28 آبان 1404 17:50
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سه شنبه, 28 آبان 1404 17:49
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سه شنبه, 28 آبان 1404 17:49
ارسال شده توسط Titan Rise Capsules
Prolonged residence of mice in spaceflight is a scientifically robust and ethically ratified model of muscle atrophy caused by
continued unloading. Under the Rodent Research Program of the National Aeronautics and
Space Administration (NASA), we assayed the large-scale mRNA and metabolomic perturbations
in the quadriceps of C57BL/6j male mice that lived in spaceflight (FLT) or
on the ground (control or CTR) for approximately 4 weeks.
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that showed inhibited networks related to protein, lipid, and carbohydrate metabolism, and adenosine triphosphate (ATP)
synthesis and hydrolysis. Finally, we discovered important upstream
regulators, which could be targeted for next-generation therapeutic intervention for chronic
disuse of the musculoskeletal system. 2020 The Authors. Journal of
Bone and Mineral Research published by American Society for Bone and Mineral Research.
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